Their musically "dirty" sound and off-the-wall sense of humor were a forerunner for the later grunge bands to come out of Seattle.

[2] The U-Men were fronted by vocalist John Bigley[3] and included Tom Price,[3] Charlie "Chaz" Ryan,[3] Robin Buchan,[3] Jim Tillman,[4] Tom Hazelmyer[5] and later Tony "Tone Deaf" Ransom.

[6] Butthole Surfers named the song "The O-Men", from the album Locust Abortion Technician, in their honor.

Jim Tillman, who is recognized as the main line-up bass player having played on the first two full releases which included the self-titled EP, "The U-Men" (1984), "Stop Spinning" (1985), and the Deep Six compilation (1986) track "They", went on to play bass for other local bands, most notably Love Battery.

[4] Mark Arm from Mudhoney noted on Sub Pop's anthology release announcement that the band was never the same after Tillman's departure.