The 2nd Infantry Regiment was redesignated as the 2nd Sub-Legion, and participated in the decisive victory over the Northwestern Confederacy at the battle of Fallen Timbers on 20 August 1794.

From Monterrey, the regiment was transferred to General Winfield Scott's command and participated in the first modern amphibious landing in American history at Vera Cruz in 1847.

After escaping from rebel forces in Texas the regiment returned to the Mid-west and fought in the Mississippi area of operations.

One member of the regiment was awarded the Medal of Honor for service during this period: 1st Lt. Marion P. Maus, 11 January 1886, Sierra Madre Mountains, Mexico.

In 1900, following occupation duty in Cuba, the regiment was preparing for shipment to China to participate in the Boxer Rebellion.

Instead, the regiment was detoured to deal with the rebellion on the Philippine Islands which had also been captured by the United States in the Spanish–American War.

Subsequently, the regiment was redeployed to garrison duties in Oahu, Hawaii and commanded by Colonel George K.

The regiment was transferred on 27 July 1921 to Fort Sam Houston, Texas, and assigned to the newly-organized 4th Infantry Brigade, 2nd Division.

In April 1933, the regiment assumed command and control of parts of the South Dakota Civilian Conservation Corps District.

After the GHQ Maneuvers the 6th Division was moved to Fort Leonard Wood, Missouri, for permanent station and arrived there on 10 October 1941.

In 1960, the 1st Battle Group, 1st Infantry was reorganized under a concept that provided sufficient tactics instructors in the permanent party for continuity, but called for outside augmentation for the summer training program.

[5] The 2nd Battalion commander Lieutenant colonel Frederick P. Mitchell blamed television newsmen and journalists for inciting the combat refusal.

Following its tour of duty in Vietnam the 2nd Battalion was sent to Fort Lewis, Washington, where it became part of the 9th Infantry Division.

In January 1991 the battalion became part of the 199th Infantry Brigade at Fort Polk, Louisiana, where it remained until inactivation in 1994.

In August 2005 2nd Battalion was deployed, along with the 172nd Stryker Brigade, to Mosul Iraq in support of Operation Iraqi Freedom.

After 12 months in Mosul 2nd Battalion was preparing to return to home station at Fort Wainwright, Alaska when their deployment was unexpectedly extended by Secretary of Defense Donald Rumsfeld.

The 2nd Battalion, along with the entire 172nd Infantry Brigade, was subsequently sent to Baghdad, Iraq to quell rising sectarian violence.

[8] The battalion was reactivated on 17 April 2007 as part of the 5th Brigade Combat Team, 2nd Infantry Division at Fort Lewis.

On 17 February 2009, President Obama ordered 4,000 soldiers of 5th Stryker Brigade Combat Team to Afghanistan, along with 8,000 Marines.

Body parts of the victims, such as finger bones and a skull were collected by the soldiers as war trophies.

[11][12] Corporal (R) Stephen Sanford, Company C, 2nd Battalion, was awarded the Distinguished Service Cross for actions in Mosul Iraq during the unit's deployment.

[13] Sergeant First Class Peter Lara, Company C, 2nd Battalion, was awarded the Silver Star for actions in Mosul Iraq during the unit's deployment.