USASOAC is responsible for service and component interface; training, doctrine, and proponency for Army Special Operations Aviation (SOA); system integration and fleet modernization; aviation resource management; material readiness; program management; and ASCC oversight.

The 22nd SWAD was activated in March 1962 at Fort Bragg, N.C: In June 1962 the unit was reorganized and redesignated as the 22nd Aviation Detachment (Special Forces).

The unit deployed to the Nha Trang, Republic of Vietnam in September 1962 to support I Corps and Special Forces with photographic intelligence.

By 9 June the following year, the newly formed company set up its headquarters inside the 5th SFG compound at Nha Trang Bay, Republic of Vietnam.

The unit's mission was to provide air movement of troops, supplies, and equipment under the direct supervision of the commanding officer, 5th SFG.

Army historians consider the 281st to be the legacy unit for today's 160th Special Operations Aviation Regiment (Airborne), abbreviated as 160th SOAR(A).

The unit earned decorations for Valor and Meritorious Service from the Army, Navy, and Republic of Vietnam.

As pilots completed training in the fall of 1980, a second hostage rescue attempt, code-named Operation Honey Badger, was planned for early 1981.

In July 2007, the regiment activated a fourth battalion to meet growing special operations forces requirements.

They employ modified heavy assault versions of the MH-47 Chinook, medium assault and attack versions of the MH-60 Black Hawk, light assault and attack versions of the MH-6 Little Bird helicopters,[6] and MQ-1C Gray Eagles via four battalions, two extended-range multi-purpose companies, a headquarters company, and a training company that are spread out between Fort Campbell, Hunter Army Airfield, and Gray Army Airfield.

Special Operations Aviation Training Company (SOATC) provisionally designated in 1992, and in 2010 officially re-designated as SOATB.