U.S. Route 11 (US 11) is a part of the United States Numbered Highway System that runs from New Orleans, Louisiana, to Rouses Point, New York.

US 11 is maintained by the Maryland State Highway Administration except for the municipally-maintained portions within the corporate limits of Williamsport and Hagerstown.

The highway crosses the Potomac River on a two-lane bridge just south of its confluence with Conococheague Creek.

At the east end of the bridge, US 11 enters the town of Williamsport, where the highway is a municipally-maintained two-lane undivided road.

The federal highway passes close to historic home Tammany and intersects Governor Lane Boulevard, which heads south through an industrial park.

US 11 passes under I-70 with no access and enters the suburb of Halfway, where the highway crosses the Winchester and Western Railroad at-grade and at an angle.

The federal highway intersects both Massey and Halfway boulevards, which head northwest toward Valley Mall.

The federal highway crosses Norfolk Southern Railway's Hagerstown District rail line immediately before its intersection with Wilson Boulevard, which heads east.

Burhans Boulevard reaches its northern end at an oblique three-way intersection with Pennsylvania Avenue.

The federal highway passes a Volvo manufacturing plant and intersects Maugans Avenue, which heads west to Maugansville.

The federal highway curves back to the northwest through an industrial area before resuming its northward course to the Pennsylvania state line.

[1][3] US 11 is the descendant of a trail blazed from Pennsylvania following the establishment of Evan Watkins's ferry across the Potomac River at the mouth of Conococheague Creek in 1744.

[4][5] In the center of the Hagerstown Valley along the trail, German immigrant Jonathan Hager laid out his namesake town in 1762.

[8] In addition, the highway's name south of Hagerstown was changed from Williamsport Pike to Virginia Avenue around 1995.

Due to the airport's east–west runway being extended eastward, US 11 was relocated by Washington County in 1964, resulting in a wide curve in what had been a straight highway.