U.S. Route 169 (also known as Mingo Valley Expressway and Pearl Harbor Memorial Expressway in the Tulsa Area) is a U.S. highway that begins in Tulsa southeast of Downtown.

Here, the freeway's interchange with 2nd Avenue also forms the eastern terminus of SH-135, an unsigned highway.

North of Collinsville, the freeway ends, and US-169 continues northeast as an at-grade highway.

US-169 Alternate follows the old route of US-169 through downtown Nowata, while mainline US-169 cuts through the eastern side of town.

East of Lenapah, it begins a concurrency with SH-10, which lasts for 4+1⁄2 miles (7.2 km) before SH-10 splits off to the west.

US-169 continues north through unincorporated Elliott, then enters the border town of South Coffeyville.