was a former segment of US 19 that ran from Bayonet Point to Brooksville, Florida, which only existed for one year.

It ran along what is today State Road 52 (SR 52) from Bayonet Point to Gowers Corner, and then turned north along US 41 into Brooksville.

Beginning at the intersection of 4th Street North (US 92 and SR 687) and 5th Avenue North in St. Petersburg, it runs west of US 19 near the Gulf coast passing through the cities of Seminole, Clearwater, Dunedin, and Tarpon Springs before ending at US 19 in Holiday, Pasco County.

It is also the unsigned State Road 595 (SR 595) throughout the entire route, and runs along much of the Pinellas Trail.

was a business route of US 19 that originally existed from Thomasville to Meigs, Georgia.

was established at least as early as 1919 as part of State Route 3 (SR 3) between the two cities.

A segment north-northwest of Thomasville had a "sand clay or top soil" surface.

[9][10] By the end of the year, the segment from the Florida state line to Thomasville was indicated to be under construction.

[10][11] In January 1932, the entire highway from Thomasville to Meigs had a completed hard surface.

is a 1.8-mile-long (2.9 km) western bypass of the city of Leesburg in Lee County, Georgia, which was completed in 2009.

from the southern end of the SR 16 concurrency to the northern terminus is part of the National Highway System, a system of routes determined to be the most important for the nation's economy, mobility, and defense.

The segment of the highway from just north-northwest of the Henry–Clayton county line to Marietta had a "completed hard surface".

[8][9] In 1953, US 19/US 41/SR 3 was shifted eastward onto the "Expressway" (the precursor of Interstate 75, or I-75) in the southern part of Atlanta, traveled west on Lakewood Avenue, and then resumed the northern path.

is a three-mile (4.8 km) business route established in 1980 that replaced the original US 19 routing through the city of Murphy, North Carolina, along Hiwassee Street, Valley River Avenue, Hill Street, Andrews Road, and Pleasant Valley Road.

U.S. Highway 19 Connector (US 19 Conn.) is a 0.72-mile (1.16 km) connector route established in October 2011 that connects US 19 (Main Street) with US 74 (Great Smoky Mountains Expressway) in Bryson City, North Carolina.

Also known as Veterans Boulevard, it was upgraded to primary status because of real need of maintenance and Swain County's secondary route budget was unable to support it.

The route is an undivided four-lane the entire length and serves as the main entrance to Bryson City.

[33] Major intersections The entire route is in Bryson City, Swain County.

U.S. Highway 19A (US 19A) was routed through downtown Waynesville, North Carolina, along with US 23A (today as US 23 Bus.).

[citation needed] U.S. Highway 19A (US 19A) was established in 1947, replacing part of North Carolina Highway 28 (NC 28), between Ela and Cherokee, North Carolina, and all of NC 293 between Cherokee and Lake Junaluska, via Soco Gap.

[citation needed] U.S. Highway 19A (US 19A) was established in 1948 when US 19 swapped routes with the previous US 19A between Ela and Lake Junaluska, North Carolina, via Soco Gap.

[37] In 1975, the relocation around Sylva was submitted to American Association of State Highway and Transportation Officials (AASHTO) for approval, but was denied by the subcommittee; despite the denial, North Carolina Department of Transportation (NCDOT) left signage as is.

[39] In 1982, NCDOT submitted a request to AASHTO to switch US 19 and US 19A between Bryson City and Lake Junaluska; but was later withdrawn before the vote.

[41][42][failed verification] U.S. Highway 19A (US 19A) was routed along Haywood Road through Asheville, North Carolina.

), established in September 1967, this 5.5-mile (8.9 km) business route follows the original US 19 mainline through the city of Weaverville, North Carolina.

The route is notable for a large, unorthodox interchange with the Penn–Lincoln Parkway (I-376/US 22/US 30) just west of the Fort Pitt Tunnel, where the route joins the Parkway and forms several wrong-way concurrencies, including one with its own opposing directions.