The highway runs through the western and northern suburbs of Philadelphia in the Delaware Valley metropolitan area, and serves as a toll-free bypass around the city, avoiding the busy traffic and congestion on Interstate 95 (I-95).

Both directions of US 202 rejoin and the route continues north as a four-lane divided highway into Chadds Ford Township, where it becomes a five-lane road with a center left-turn lane and runs through more commercial areas.

The route comes to an intersection with US 1/US 322 (Baltimore Pike) in the community of Painters Crossing, where US 322 heads east along US 1 and turns northwest for a concurrency with US 202.

The road runs past more homes and commercial establishments, coming to a jughandle-controlled intersection at Stetson Middle School Drive/Skiles Boulevard.

The route heads north-northeast near more business parks before it runs near wooded neighborhoods and reaches a diamond interchange at Boot Road.

Following this, the freeway continues east-northeast near commercial development before crossing into Tredyffrin Township and running through wooded areas with nearby residential neighborhoods, with the Chester Valley Trail parallel to the south.

Farther east, the route comes to a northbound exit and southbound entrance at Swedesford Road that provides access to PA 252.

Following this, the frontage roads end and the route runs east-northeast past office parks with the trail to the south.

The freeway comes to a northbound exit providing access to eastbound I-76 (Schuylkill Expressway) and Devon Park Drive and a southbound entrance from Swedesford Road.

[3][5] Past the US 422 interchange, the US 202 freeway enters Upper Merion Township in Montgomery County and continues into the community of King of Prussia.

The route heads into business areas and intersects Gulph Road, at which point it passes southeast of the King of Prussia shopping mall.

The route runs between commercial establishments to the northwest and residential areas to the southeast, coming to a bridge over the Pennsylvania Turnpike (I-276).

From here, the route becomes East Dekalb Pike and runs through more commercial areas, crossing the Chester Valley Trail and bending to the north-northeast.

Southbound US 202 heads south along the four-lane divided highway from the Schuylkill River into Upper Merion Township through wooded areas with nearby commercial development, passing over the Harrisburg Line before coming to a southbound exit to PA 23 and a northbound entrance from Ross Road, with this interchange utilizing a portion of the incomplete Schuylkill Parkway freeway stub.

Past this, southbound US 202 crosses over the Chester Valley Trail and re-enters Upper Merion Township as it passes under Boro Line Road.

[3][6] From here, US 202 heads northeast into East Norriton Township along two-lane undivided Dekalb Pike, passing through suburban residential neighborhoods and running through the community of Grand View Heights.

The road continues into business areas and passes to the southeast of Suburban Community Hospital, widening into a four-lane divided highway and coming to an intersection with Germantown Pike.

The route continues past a mix of residential and commercial development and comes to a bridge over the Pennsylvania Turnpike Northeast Extension (I-476).

[3][6] US 202 becomes a four-lane divided highway and comes to an intersection with the southern terminus of US 202 Bus., where that route heads north on Dekalb Pike.

At this point, the trail heads to the west side of US 202 and the parkway continues into Doylestown Township, curving east and coming to the 1st Lt. Travis L. Manion Memorial Bridge over the Neshaminy Creek.

US 202 continues along the parkway past residential subdivisions and crosses under Wells Road before it curves northeast, heading northwest of Doylestown Central Park.

Past this intersection, the road becomes two-lane undivided Doylestown Buckingham Pike and it heads east-northeast through a mix of wooded residential neighborhoods and some fields, bending to the east and crossing Watson Creek.

Here, the route turns northeast and becomes a two-lane undivided road, passing near more development as it heads through the northwest corner of New Hope.

US 202 comes to a two-way ramp called US-202 Spur that heads east to provide access to PA 32, at which point US 202 curves north into Solebury Township and runs near development.

At the time, US 202 ran on local roads from the West Chester borough to Paoli, then forming a brief concurrency with US 30 before turning north onto present-day PA 252 to King of Prussia.

However, environmental concerns, local opposition, and continued development along the US 202 corridor in Bucks and Montgomery counties prevented further construction of the expressway.

Also included in the project was the reconstruction of the Chesterbrook Boulevard and PA 252 interchanges, along with the relocation of the King of Prussia Inn, which had sat isolated for years in the median of US 202.

[27] The American Association of State Highway and Transportation Officials (AASHTO) Special Committee on U.S. Route Numbering approved the US 202 Bus.

Additionally, a $130 million project was planned to widen the roadway from Johnson Highway on the border of Norristown and East Norriton Township to PA 309 in Montgomeryville in Montgomery County.

Further improvements to this section of the highway began in 2017 and were completed in 2019, with the rehabilitation of the Morstein Road overpass and the twin bridges over Amtrak's Keystone Corridor rail line taking place.