[2] US 29 begins its northward journey at an intersection with US 90 and US 98 in downtown Pensacola along North Palafox Street, which starts off as a four-lane undivided concrete boulevard, with occasional provisions for center-left turn lanes.

After the intersection with SR 296, the name of US 29 changes to Pensacola Boulevard, and North Palafox Street moves onto its former routing along CR 95A, which it will maintain until it reaches Ten Mile Road.

After the western terminus of SR 742, US 29 encounters a massive interchange with Interstate 10 at exits 10A and 10B, which includes loop ramps, flyovers, and an unusually wide median, all of which is on the border between Brent and Ensley.

Before entering Cantonment, CR 95A merges with US 29 just south of the grounds of a large International Paper factory across the street from that intersection, where the road becomes a four-lane undivided highway.

North of there, the road descends slightly over a culvert over a tributary of Cowdevil Creek but then elevates through a wooded area which ends at some farmland at the top of this ascension.

The road passes by an Escambia County sheriff's station on the northeast corner of Omega Avenue and later dips again as it approaches the culvert over the Dry Creek just south of a blinker-light intersection with CR 182.

From there, the forest on the east side evolves into farmland until it approaches SR 97 which spans southeast to CR 95A and northwest to Atmore, Alabama.

Northeast of those powerlines, the road enters Bogia, where it intersects two local streets named for the community and a pair of bridges over Cotton Creek.

After the intersection with Brown Road, US 29 begins to run down a hill and later curves to the right where it crosses over a pair of bridges over Canoe Creek, then enters Bluff Springs, which appears to be more residential than communities further to the south, but is not lacking in woodlands or farmlands either.

At the intersection of Dawson Road, some reduce speed warning sings can be spotted for the northbound lanes, showing a sign of the end of rural high-speed travel.

The shield for US 29 was red with white lettering and outline, until the state was forced by the federal government to conform to standards that required consistent black-and-white signs in 1993.