U.S. Route 70 (abbreviated US-70) is a transcontinental U.S. highway extending from Globe, Arizona to Atlantic, North Carolina.

It serves the cities of Ardmore, Durant, Hugo, and Idabel, as well as Tillman, Cotton, Jefferson, Carter, Marshall, Bryan, Choctaw, and McCurtain counties.

The highway's initial path (which entered the state in Cotton County, further east than it does today) included several deviations from the present-day route, serving Walters and following a more northerly course between Ardmore and Madill.

US-70 enters Oklahoma in Tillman County, crossing the Red River from Texas, concurrent with US-183.

It leaves Davidson, passing south of the Hackberry Flat Wildlife Management Area.

The two highways proceed east from this junction, leaving Tillman County, US-70 having traveled for 30.78 miles (49.54 km) within its boundaries.

[3] US-70/SH-36 pass into Cotton County, heading southeast along the southern limit of Devol, which is served by SH-70B, a spur from US-70.

US-277 and US-281 exit the Interstate at this point, forming a triple concurrency with US-70 as it continues east toward Randlett.

At the southeast corner of the Randlett limits, US-277/US-281 turn north, while US-70 continues on its due east course.

Leaving town, it proceeds due east across unincorporated Jefferson County for about 21 miles (34 km).

[6] US-70 heads due east on an arrow-straight route for the next 22+1⁄2 miles (36.2 km) across Carter County.

US-70 heads east, passing along the southern edge of Mead, then enters the city of Durant, the county seat.

US-70 heads northeast out of Bennington, then turns back to a due east course to enter Choctaw County.

[10] The first town US-70 serves in Choctaw County is Boswell, where it junctions with SH-109 at that highway's western terminus.

The two highways come to an interchange with the Indian Nation Turnpike on the western outskirts of the county seat, Hugo.

[11] This marks the end of the freeway; US-70 continues east as a four-lane divided highway with at-grade intersections.

The highway then leaves Hugo, passing through unincorporated Fallon and entering Sawyer, where it forms the southern terminus of SH-147.

[8] US-70 was originally designated in Oklahoma on December 7, 1926, as part of the initial slate of U.S. highways established through the state.

The old alignment from west of Randlett, through Emerson and Walters, to Comanche, was given the additional designation of U.S. Route 70N on September 1, 1936.

This was remedied on September 10, 1951, with the three highways being shifted to a path following a straighter southeasterly course between the two towns.

[1][18] SH-70A (7 mi) is a spur connecting Kingston, Oklahoma to Woodville, McBride, and Lake Texoma.

SH-70D is a spur to Devol SH-70E runs parallel to US-70 starting at SH-78 and traveling east, looping north to connect to its parent route near Bennington.