[6] However, Ortega pulled out of the fight with a knee injury and was replaced by former UFC Lightweight Champion Frankie Edgar.

[10][11] The pairing was originally scheduled for UFC 249, but Gane was forced to pull out of the event after he suffered a pneumothorax in training.

[13] The bout fell through once again as Abdurakhimov pulled out due to undisclosed reasons on September 28 and Gane was expected to face promotional newcomer Ante Delija.

[14] However, that bout was also cancelled on October 14 due to contractual issues with Delija, seemingly related to his previous deal with the PFL.

However, it was announced on October 4 that Salikhov pulled out due to undisclosed reasons and was replaced by James Krause.

[23] A middleweight bout between Krzysztof Jotko and Makhmud Muradov was briefly scheduled to take place at this event, before being moved two weeks later to UFC Fight Night: Hall vs.