[2] A bantamweight bout between Pedro Munhoz and former UFC Lightweight Champion Frankie Edgar served as the event headliner.

[3] Promotion officials had initially targeted a welterweight bout between former UFC Welterweight Champion Tyron Woodley and former interim champion Colby Covington to serve as the event headliner, but Woodley announced that the date did not provide him with time suitable enough to prepare because of injuries incurred during his most recent fight.

[10] Just hours before the event was scheduled to begin, it was announced that the bout was cancelled due to Saint Preux testing positive for COVID-19.

[12] Former UFC Middleweight Championship challenger (as well as 2000 Olympic silver medalist and former world champion in freestyle wrestling) Yoel Romero was scheduled to face Uriah Hall at the event, but pulled out of the fight on August 11 for undisclosed reasons.

[17] A light heavyweight bout between Jorge Gonzalez and Ike Villanueva was expected to take a week earlier at UFC 252.

[19] In turn, Gonzalez was removed from the card for undisclosed reasons and replaced by promotional newcomer Jordan Wright.

Despite making the required weight, Sato was not cleared to fight by Nevada State Athletic Commission (NSAC) medical personnel and Rodriguez faced Grant instead.

[24] However, promotion officials elected to move the pairing a week later to UFC Fight Night: Smith vs. Rakić for undisclosed reasons.