[2] The promotion was targeting a middleweight bout between former UFC Welterweight Championship challenger Darren Till and Jack Hermansson to serve as the event headliner.

[5] Marvin Vettori, who was expected to face former Strikeforce Middleweight Champion Ronaldo Souza a week later at UFC 256, served as his replacement.

[7] John Allan and Roman Dolidze were originally scheduled to meet at UFC 255 in a light heavyweight bout.

[12] The new booking fell through on November 19, as it was revealed that Barcelos was removed from the contest due to a medical suspension related to his latest bout at UFC on ESPN: Santos vs.

[19] Just hours before the event, the UFC decided to remove the fight after one of De La Rosa's cornermen tested positive for COVID-19.

[26] The latter was due to a non-COVID related medical issue with Durden, before being rescheduled for UFC Fight Night: Thompson vs.