UFC on ESPN: Ngannou vs. dos Santos (also known as UFC on ESPN 3) was a mixed martial arts event produced by the Ultimate Fighting Championship that was held on June 29, 2019, at Target Center in Minneapolis, Minnesota, USA.

[2][3] The event was the promotion's third visit to Minneapolis and the first since UFC on FX: Browne vs. Bigfoot in October 2012.

[7] A light heavyweight bout between Roman Dolidze and Vinicius Moreira was scheduled to take place at the event.

[11] On September 5, 2019, it was reported that Murdock had received a 20-month suspension by USADA, having tested positive for GW1516, better known as Cardarine and often sold on the black market as Endurobol, on a sample collected on July 6, 2019.

[12] Later in 2019, Murdock revealed that the reason behind withdrawing from the bout was initially high grade stenosis which was later diagnosed as Moyamoya disease.