USCGC Agassiz (WSC-126) later WMEC-126, was a steel hulled, single screw Active-class patrol boat of the United States Coast Guard which served between 1927 and 1969.

[1] They were meant to be able to stay at sea for long periods of time in any kinds of weather, and were able to expand berthing space via hammocks of the need arises, such as if a large amount of survivors were on board.

The cutter was laid down on 24 July 1926 as yard number 321 and launched on 30 November 1926 from slipway L.[3] The ship was commissioned on 12 January 1927.

In January 1956 the Agassiz aided in the disabled Manitou 275 miles (443 km) southeast of Cape Henry, Virginia.

The disabled Canadian fishing vessel Clara and Linda was aided 160 miles (260 km) east of New York in 1967 during a storm.