[2][3] Sebago was initially stationed at San Francisco, California but was transferred soon thereafter to Norfolk, Virginia, where she served out of from 1 November 1945 to 1 June 1946.

The vessel was subsequently moved to Mobile, Alabama, where she was used for law enforcement, search and rescue, and Campeche Patrol until July 1964.

A Coast Guard press release noted that "On patrol, the SEBAGO is ever ready to render medical aid, assist disabled boats through effecting repairs or provide a tow into port.

She completed twenty-two assistance missions, saved a half-million dollars worth of shipping and obtained medical care for four sick or injured seamen.

The cutter also completed her annual overhaul in the Coast Guard Yard at Curtis Bay, Maryland, in February 1959.

Sebago was refurbished at a cost of $179,000 at the Alabama Drydock and Shipbuilding Company from 29 September to 31 October 1968 in preparation for assignment to Vietnam.

Combat operations Sebago was assigned to Coast Guard Squadron Three, South Vietnam, serving in theatre from 2 March to 16 November 1969, while under the command of CDR Dudley C. Goodwin, USCG.

On 18 and 19 December 1969, Sebago placed a damage-control party on board M/V Jody Re, brought the flooding under control, and stood by until a commercial tug arrived.

On 20 December 1969, she stood by the grounded Danish M/V Helle 25 miles northeast of Cabo Falso until a commercial tug arrived.