USCGC Escanaba (WHEC-64) was an Owasco-class high endurance cutter built for World War II service with the United States Coast Guard.

She was home ported at Alameda, California, from 1946 to 1954, and used for law enforcement, ocean station, and search and rescue operations in the Pacific.

In late November 1965, she assisted the US MV's American Pilot and Maumee Sun following their collision west of Cape Cod Canal.

On 11 January 1966, she rescued two survivors from MV Monte Palomares after that ship sank in heavy seas with the loss of 32 lives.

The six men that were stranded on the bow section, as well as one seaman of SS Platte who disappeared during an attempted rescue of Ragny's crew, perished in the accident.