SS Mission Solano was a Type T2-SE-A2 tanker built for the United States Maritime Commission during World War II.

Originally laid down as SS Mission Solano on 8 October 1943 as a Maritime Commission type (T2-SE-A2) tanker hull under Maritime Commission contract (MC hull 1277) by Marine Ship Corporation, Sausalito, California; launched on 14 January 1944; sponsored by Mrs. William B. Hawke and delivered on 30 March 1944.

Chartered to Deconhill Shipping Company for operations, she spent the remainder of the war carrying fuel to US forces in the western Pacific.

When the newly created Military Sea Transportation Service took over operational control on 1 October 1949 she was redesignated USNS Mission Solano (T-AO-135).

This article incorporates text from the public domain Dictionary of American Naval Fighting Ships.