2W3C861556041ENSG00000138768ENSMUSG00000029407O60763Q9Z1Z0NM_001290049NM_003715NM_019490NP_001276978NP_003706NP_062363General vesicular transport factor p115 is a protein that in humans is encoded by the USO1 gene.

[5][6][7][8][9][10] The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase.

Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum (ER), where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus.

Transport from the ER to the cis/medial Golgi compartments requires the action of this gene product, GOLGA2, and giantin in a sequential manner.

This article on a gene on human chromosome 4 is a stub.