USS Commodore McDonough was a ferryboat acquired by the Union Navy during the American Civil War.

Throughout her service, she operated in South Carolina waters, primarily off Charleston, but often cruising up the many rivers of that coast to bombard shore installations, cover the landing of troops, engage Confederate batteries, and perform reconnaissance.

In the continuing operations in Charleston Harbor, she frequently bombarded the forts protecting the city.

At the close of the war, she assisted in harbor clearance at Port Royal, South Carolina, and on 23 August 1865 — while under tow for New York — she foundered.

This article incorporates text from the public domain Dictionary of American Naval Fighting Ships.