Guiding virtually defenseless merchant ships through coastal and Caribbean waters patrolled by U-boats, Herbert carried out frequent depth charge attacks on marauding submarines.

Herbert now APD-22 sailed for the Pacific, reaching San Diego for amphibious training and continuing on to Cape Sudest, New Guinea, via Pearl Harbor 23 March 1944.

Troops landed under naval cover to secure the airfield, which was within easy striking distance of the Philippines, next major step in the island-hopping war across the Pacific.

From the Philippines, Herbert moved north for escort duty to Iwo Jima, returning to Leyte 18 March 1945 to prepare for the invasion of Okinawa, the largest amphibious operation of the Pacific war.

Herbert was decommissioned at San Diego on 25 September 1945, stricken from the Naval Vessel Register on 24 October 1945 and sold for scrap to the Boston Metal Company of Baltimore in Maryland on 23 May 1946.