Following the entry of the United States into World War II, his squadron was dispatched to the Aleutian Islands for the aviation buildup in the North Pacific.

Arriving Boston, Massachusetts, on 12 June 1945 from her final transatlantic mission, the destroyer escort prepared for service in the Pacific.

She transited the Panama Canal 2 August and was en route to Pearl Harbor when she received news of the Japanese surrender.

Lansing returned New York 26 September, and decommissioned at Green Cove Springs 25 April 1946, joining the Atlantic Reserve Fleet.

Upon her return to the Navy in 1954 Lansing was converted to a radar picket escort ship and given the hull classification symbol DER-388 21 October 1955.