Following a Bermuda shakedown, Moale remained on the Atlantic coast conducting experimental tests and training precommissioning destroyer crews.

On 21 August, she rendezvoused with the newly commissioned Missouri, Alaska, and Destroyer Division 120 (DesDiv 120) and got underway for Trinidad in the British West Indies, whence she continued to the Panama Canal Zone, and, thence to San Pedro, California.

Reporting to the Commander Destroyers, Pacific Fleet (ComDesPac), at Pearl Harbor, 15 September, she underwent carrier screening, night firing, and shore bombardment exercises until 23 October.

On 2 December 1944, she was joined by the destroyers Allen M. Sumner and Cooper for a midnight raid of enemy troop reinforcement at the western Leyte port of Ormoc.

The enemy destroyer Kuwa was sunk by gunfire from the three ships, but Take torpedoed and sank Cooper with the loss of 191 crewmen and 13 officers.

She then returned to Leyte, whence she joined the 5th Fleet and steamed back to Ulithi to resume operations with the Fast Carrier Forces, now designated TF 58.

1 mount during heavy seas with 40-foot (12 m) swells, Moale departed the Volcano Islands, 25 February, and sailed eastward for repairs at Pearl Harbor.

Through 27 June she served on radar picket stations, where danger remained present and alerts still frequent, even though the pressure was not as great as in April and May.

On 28 June, Moale departed for Leyte, where she joined Task Group 32.12 of the Third Fleet and returned to Okinawa to act as part of the covering force for minesweepers in Operation Juneau.

She then deployed to the western Pacific for 6 months prior to reporting to the Fleet Sonar School at San Diego for duty as a training ship.

Arriving at Norfolk at the end of April, she participated in training exercises in the western Atlantic until November 1950, when she sailed eastward for her first 6th Fleet deployment.

Similar operational schedules, alternate east coast and Mediterranean duties, were followed until 24 April 1953, when Moale departed on an around-the-world voyage.

From 1954, into 1969, Moale's employment schedule included operations in the Atlantic, North Sea, and the Caribbean, with regular rotation to the Mediterranean for duty with the 6th Fleet.