USS Nathan Hale (SSBN-623) was the sixth Lafayette class nuclear-powered fleet ballistic missile submarine produced.

She was named for Captain Nathan Hale (1755–1776), a Connecticut schoolteacher who served in the Continental Army and known most famously for giving his life as a spy during the American Revolutionary War.

Nathan Hale entered service on 21 May 1964 with her home port at Charleston, South Carolina, and performed deterrent patrols as a member of the United States Atlantic Fleet.

In the period 1967-68 she underwent overhaul and refueling, and was subsequently transferred to the Pacific Fleet, home ported in Pearl Harbor, Hawaii, and operating out of Agana, Guam.

Ex-Nathan Hale entered the Navy's Nuclear-Powered Ship-Submarine Recycling Program at Bremerton, Washington on 2 October 1991.