She returned to Pearl Harbor on 28 March 1946 and was assigned to Joint Task Force 1 for "Operation Crossroads", the 1946 atomic bomb test series at Bikini.

Three days later she sailed to Qingdao to commence a series of patrol, escort, search and rescue, ASW, and hydrographic survey missions and exercises along the China coast and off Taiwan and Okinawa.

Redesignated a radar picket destroyer in 1950, she conducted her scheduled operations as DDR–883 until 1964 when Newman K. Perry underwent the FRAM I refit at the Boston Naval Shipyard until February 1965.

Departing Newport with Destroyer Division 201 on 4 October, she transited the Panama Canal, stopped in Hawaii, Japan, Okinawa and the Philippines, and arrived on station in the Mekong Delta of South Vietnam on 23 November.

Other assignments on that tour with the 7th Fleet took her along the coast to the DMZ and then to the Gulf of Tonkin for plane guard and search and rescue missions.

After overhaul at Boston, Newman K. Perry began 1968, with Caribbean exercises and on 4 April departed Newport for the Mediterranean to resume her annual deployments with the 6th Fleet.

In the 1971 Newman K. Perry was assigned to the Naval Reserve Force (NRF) as a unit of Destroyer Squadron 28.

In Oct 1974, she hit a buoy foundation in NY harbor, opening a hole in the scoop injection of the forward engine room.