Located in the southern part of the region, it is bordered by the City of Brussels, Forest, Ixelles, and Watermael-Boitsfort, as well as the Flemish municipalities of Drogenbos, Linkebeek and Sint-Genesius-Rode.

According to legend, Uccle's Church of St. Peter was dedicated by Pope Leo III in the year 803, with Charlemagne and Gerbald, Bishop of Liège, attending the ceremony.

In 1467, Isabella of Portugal, wife of Philip the Good, Duke of Burgundy, founded a Franciscan convent on Uccle's territory.

Throughout the early stages of its history, however, the village of Uccle always had a predominantly rural character and lived mostly from the products of forestry and agriculture.

However, in 1465, Marguerite Hinckaert wife of Louis de Mailly, obtained from the sovereign the annexation of this fief to the Lordship of Stalle.

Large 19th- and 20th-century villas with generous gardens make this green and calm suburb a favourite with well-off expatriates, with the Art Deco area around the Royal Observatory of Belgium and the fringes of the Sonian Forest the two most desirable addresses.

The Place de Saint-Job/Sint-Jobsplein and the area near St. Peter's Church and the Municipal Hall are two older parts of town, now filled with a happy mix of stores and pubs.