[1] After receiving a holiday special one-shot and appearing as a secondary character in a Howard the Duck story, entitled "Ms. Poole if You're Nasty", Marvel announced the release of Unbelievable Gwenpool in December 2015, retaining the core creative team of Christopher Hastings and Gurihiru who had developed the Gwenpool holiday one-shot.

[2] The series debuted in June 2016, and released a special #0 issue along with Unbelievable Gwenpool #2 that collected the character's Christmas and Howard the Duck adventures.

[3] Critics generally praised Hastings' writing (noting that he did not bog down the character in origin stories), and especially the art from Gurihiru.

[4][5] Kinja's Observation Deck wrote favorably of the last issue, where Gwen Poole converses with other characters outside the fabric of reality in an effort to understand her actions, saying that the series finale demonstrated the "incredible power of comic books.

[9] In 2021 Marvel Cinematic Universe (MCU) film Spider-Man: No Way Home, the initial spell Peter Parker attempts to have Doctor Strange cast to make the world forget he is Spider-Man, and the spell he ultimately later has Strange cast alongside the barriers of the multiverse to make his existence completely forgotten to the entire world, are respectively adapted from The Amazing Spider-Man storyline "One Moment in Time" and the Unbelievable Gwenpool storyline "Believe It", introduced as a spell Gwen has Strange cast to make her original world forget her existence; Strange additionally compliments Benedict Cumberbatch's portrayal of him in the original storyline.