In June 2015, following the popularity of Spider-Gwen, all Marvel titles being published had alternate covers with Gwen Stacy reimagined as other characters, such as Doctor Strange, Groot and Wolverine.

[2] After seeing how many fans were cosplaying as a character who was not even featured in any comic, Marvel editor Jordan White approached writer Christopher Hastings and editor Heather Antos with the task of creating a story around her, with the stipulation of the character being wholly unrelated in backstory to either Deadpool or Gwen Stacy (keeping her film and television rights at Marvel Studios, instead of at 20th Century Fox or Sony Pictures).

[7][8] The Howard the Duck arc, from November 2015 to January 2016, was drawn by Brazilian artist Danilo Beyruth, and the holiday special, published in December 2015, had art by Japanese duo Gurihiru.

Gwenpool joins MODOK's elite squad, which also includes the alchemist Mega Tony, the magician Terrible Eye, and Batroc the Leaper, who gives Gwen basic combat and firearms training.

Doctor Strange agreed to transfer her history from Gwen's original world to create a fake background for her in the Marvel Universe, so that she could get her Social Security number, driver's license and other essential documents.

[21] During the Civil War II storyline, Gwenpool appears in Georgia attempting to earn the bounty on an alien smuggler named Chammy, only to discover that Rocket Raccoon and Groot are also after him.

Gwen refuses to help at first, under the logic that Captain Marvel, being one of the most important "characters" in the current "story", would not be killed off in "a comic about a talking tree and raccoon".

[22] After short team-ups with the Champions,[23] Blade,[24] Deadpool,[25] and the duo of Ghost Rider and Kate Bishop[26], Gwen meets her brother Teddy, who drags her back to her world (or a close facsimile).

Watching the past from outside the borders, Gwen sees the "extra pages" of her Holiday Special, in which when her brother Teddy was sucked into the Marvel Universe, he ended up working for Orto the snake swordsman.

Upon seeing her kill Orto's henchmen, Teddy runs into versions of Spider-Man, The Terrible Eye, and Vincent Doonan, who claim to be from a future where Gwen becomes a huge threat and destroys their lives.

[30] Along with the other Avengers, Gwen helps stop giant monsters created by the original M.O.D.O.K., adopts a baby land-shark she names Jeff, and faces an alliance of villains headed by Madame Masque.

[31] Later, during the War of the Realms storyline, Gwen and the West Coast Avengers assist Otto Octavius in protecting San Francisco, and she uses her perspective as a Marvel Universe outsider and a fellow B-list hero to help him come to terms with his lack of a star role in the event.

[34] After accidentally setting herself to combat the Immortal Hulk, Gwen pulls previous versions of herself, as portrayed by different writers and artists, from the Gutter, forming a six-Gwen team known as the GwenHive.

[15] After leaving Jeff with Wade while dressed in her original Chris Bachalo design,[36] Gwen later avoids participating in a Fortnite tie-in while drinking with Kwannon, Mystique, Storm and Domino.

[38] Gwen is later seen wearing cosplay for a fan convention,[39] and is also seen in Los Angeles celebrating the repeal of Kamala's Law with Robbie Reyes and the West Coast Avengers,[40] and leaves a mug with her face on it to Kate as a parting gift.

In Gwenpool Strikes Back, she learned she now has Evil Gwen's reality-manipulating power to alter history by "recalling" flashback sequences, retroactively causing them to have happened.

While untrue, Gwen decides to accept this theory as Marvel Universe reality, allowing her to live care-free in the mutant nation of Krakoa without her presence being questioned.

Terrible Eye: Gwen's only girl friend on the merc crew they were all forcibly forced to join she has a mask that allows her mystical access to knowledge beyond the ken of man.

He had a hard time adjusting to life in the super community when their mercenary team fell apart, but Gwen helped get him a job working for Peter Parker.

When Gwen expressed a desire for supervillainy he helped her Robin Hood some gold from an illegal casino, making her independently wealthy and no longer needing to worry about money, at least for a while.

Meaning not only do the inside jokes she makes cut a LOT deeper than other stories of this nature, but it leads to some shocking moments like when her first friend dies a bloody gory death, and she realizes that the guy isn't popular enough to convince Marvel to bring him back so he's likely gone for good.

Armed with all the skills a partially-viewed YouTube how-to video can supply, Gwenpool goes up against a villain who's more akin to an evil version of the genie in Disney's "Aladdin" than any kind of real threat, but—as scripted by Hastings and illustrated by Gurihiru with a touch of manga influence—the story is too much fun not to like.

"[66] Jesse Schedeen of IGN gave Gwenpool Holiday Special #1 a grade of 7.5 out of 10, writing, "The Deadpoool/Hawkeye team-up from Gerry Duggan and Danilo S. Beyruth is probably the most well-rounded of the bunch.

[...] There's a kind of uncertain demeanor to "The Unbelievable Gwenpool" #1, where Hastings begins to explore his character in earnest while remaining vague about the concept's longterm workability.

Gwenpool has always been a relatively bright, vibrant character -- a figure leading a bubblegum pop tour of the Marvel Universe -- and the art team more than delivers from medium-bending monologues to the reader to a back-and-forth exchange between Gwen and Spidey fresh off the heels of a gun-toting bank robbery.

Wonderfully weird and a clear labor of love from the creative team, the new miniseries repositions Gwenpool as the wackiest new Marvel character in recent memory.

From dabbing to memes, the heroine rightly calls herself a queen of cringe culture, but it somehow works with this debut's issue as Gwen acts against a clean-cut Peter Parker.

[28] Dark Gwen would return as the main antagonist of the video game Marvel Duel, and make a cameo appearance in Peter Parker & Miles Morales: Spider-Men Double Trouble, attending a villain convention with Batroc the Leaper.

[82] An alternate universe's version of Gwen merges with a Venom Symbiote that has unique medium awareness and knowledge of the Marvel Multiverse,[83] but is killed and absorbed by the "Poisons" of Venomverse.

Gwen is hired by Moon Knight and the Punisher to find the location of evil versions of Magneto, the Red Skull, the Abomination and Doctor Doom, who are controlling Deadpool to kill that Marvel Universe's heroes.