The Union School in Natchez was the first public, co-educational school by the city for African American students formed in 1871 and closed c. 1925, and was located at the southeast corner of North Union and Monroe Streets in Natchez, Mississippi.

[2][3][4] The Union School was established in 1871 as a brick building and it had thirteen rooms which held up to 948 children.

[5] The school opened in the fall of 1871, led by Theodore H. Greene and employed 9 black teachers, with the enrollment of 406 students.

[8] In 1924, the lower grade levels had as many as 120 students in a single classroom, which prompted the school board to plea with the mayor to make changes.

The school is included in the "African American Public Education, Natchez Trails" historical marker at its former site.