United States drug overdose death rates and totals over time

The United States Centers for Disease Control and Prevention (CDC) has data on drug overdose death rates and totals.

Synthetic opioids other than methadone (primarily fentanyl) were involved with 70,601 deaths in 2021.

[4][5][6][1][2] Around 94,100 people died in the 12-month period ending July 31, 2024, at a rate of 257 deaths per day.

CDC: "Predicted provisional counts represent estimates of the number of deaths adjusted for incomplete reporting (see Technical Notes)."

[1] For convenience, and as a geographic aid, the "Category:Health in STATE" links are also in this map.

[7] See map higher up for states with the highest overdose death rates.

Drug overdose deaths in the US per 100,000 people by state. ^{[

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A two milligram dose of fentanyl powder (on pencil tip) is a lethal amount for most people. ^{[

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U.S. yearly overdose deaths from all drugs. ^{[

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US yearly overdose deaths, and the drugs involved. ^{[

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Fentanyl . 2 mg (white powder to the right) is a lethal dose in most people. ^{[

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Three waves of opioid overdose deaths. ^{[

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U.S. overdose deaths involving all opioids . Deaths per 100,000 population. ^{[

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US yearly deaths from all opioid drugs. Included in this number are opioid analgesics, along with heroin and illicit synthetic opioids . ^{[

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US yearly deaths involving other synthetic opioids , predominately Fentanyl . ^{[

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US yearly deaths involving prescription opioids. Non-methadone synthetics is a category dominated by illegally acquired fentanyl , and has been excluded. ^{[

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US overdose deaths involving heroin , by other opioid involvement. ^{[

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Timeline of US overdose deaths involving stimulants ( cocaine and psychostimulants ), by opioid involvement. ^{[

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US overdose deaths involving psychostimulants with abuse potential (primarily methamphetamine ), by opioid involvement.

Opioid involvement in cocaine overdose deaths. ^{[

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The top line represents the yearly number of benzodiazepine deaths that involved opioids in the US. The bottom line represents benzodiazepine deaths that did not involve opioids. ^{[

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Drug overdose deaths involving antidepressants , by opioid involvement. ^{[

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Timeline of US drug overdose death rates by race and ethnicity. ^{[

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Timeline of US drug overdose death rates by sex, ^{[

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Drug overdose death rates for European countries. ^{[

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