Entertainers such as Cats, Chespirito, Mayumaná, Emma Shapplin, Los Vivancos, Raphael, José Luis Perales, Paloma San Basilio, and Bajofondo have performed there.

In tribute to the originator of the project, the theater was baptized "Gabriel Botero Obregón" in 1988.

Initially, the theater was for exclusive use by the University, but as it became larger, the school made it available for public performances.

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