[1] Graduate medical education programs are located in Chattanooga, Knoxville, and Nashville; family medicine centers in Jackson, Knoxville, and Memphis; dentistry clinics in Bristol, Jackson, and Union City, as well as public and continuing education programs across the state.

The Health Science Center is part of the statewide, multi-campus University of Tennessee system.

The center educates on sterile product preparation, develops a basis for parenteral medications, and provides services to the pharmaceutical industry and individuals.

Areas of emphasis are the university's research efforts, which receive nearly $100 million in yearly grants from the National Institutes of Health and private foundations.

The college offers a full range of advanced training in prosthodontics, oral surgery, endodontics, periodontics, orthodontics, and pediatric dentistry, and a two-year program in dental hygiene.

It offers programs of study in audiology and speech pathology on the Knoxville campus and clinical laboratory sciences, health informatics and information management (online program), occupational therapy, and physical therapy on the Memphis campus.

The UTHSC pediatric residency program is affiliated with Le Bonheur Children's Medical Center, and residents in pediatrics, radiology, and other fields spend time working at St. Jude Children's Research Hospital in Memphis.

The college also operates the UTHSC College of Medicine Mobile Stroke Unit, the world's first mobile stroke unit with advanced CT imaging capabilities, including CT angiography imaging for the brain and blood vessels.

The institute was named for the family of Ralph S. Hamilton, MD, a professor, and physician with the department, who contributed $6 million toward its construction.