It extends to campuses in the Texas border communities of Laredo and the Lower Rio Grande Valley.

[5] State Senator Leticia Van de Putte championed the creation of a special advisory group that would research the benefits of a possible merger between the Health Science Center and the University of Texas at San Antonio (UTSA), which is also located on the city's northwest side.

[11] In 2010, the special advisory group, headed by Peter T. Flawn, former president of both UTSA and the University of Texas at Austin, concluded that a merger would not be in the best interest of the two institutions.

[12] Among its key arguments were that both institutions had strong leadership already on a positive trajectory, the merger would be a short-term distraction for UTHSCSA, and the benefit to UTSA's national stature would be slight.

[13] The $300 million project, titled "The Campaign for the Future of Health", seeks to build new infrastructure with the South Texas Research Facility and the President's Excellence Fund.