He is fluent in Italian and French languages and is mostly known for starring or appearing in many horror, fantasy and drama films, including the cult classic Dèmoni (Demons).

His most recognized role in the English-speaking countries was in his work in Dario Argento's film Opera though in the English dubbing, his voice was replaced with another actor's deeper voice.

The only DVD that retains his original voice on the English dub is the UK release from Arrow Films.

[citation needed] In 2024 he published his first book, La bellezza nel destino.

[2] Urbano Barberini is married to Viviana Broglio and has a son; he considers himself Roman Catholic.