Urine cytology

The test commonly checks for infection, inflammatory disease of the urinary tract, cancer, or precancerous conditions.

It is especially recommended when blood in the urine (hematuria) has been detected.

Urine typically contains epithelial cells shed from the urinary tract, and urine cytology evaluates this urinary sediment for the presence of cancerous cells[2][3] from the lining of the urinary tract, and it is a convenient noninvasive technique for follow-up analysis of patients treated for urinary tract cancers.

For this process, urine must be collected in a reliable fashion, and if urine samples are inadequate, the urinary tract can be assessed via instrumentation, such as a catheter.

One limitation, however, is the inability to definitively identify low-grade cancer cells and urine cytology is used mostly to identify high-grade tumors.

The Paris System for reporting urine cytology, version 2.0, ranging from negative to positive for high grade urothelial carcinoma . [ 1 ]