Opened in 1958 after a decade of planning,[1] Uxbridge Hospital has undergone renovations with additions in 1967 and 1996 to 1998 (covered area at the main entrance and interior renovations).

[2] The hospital has a helipad located west of the main wing for transfers out of Uxbridge and a walkway connecting to Testa Professional Building at 2 Campbell Drive.

[4] In April 1997, under the Common Sense Revolution, the hospital was amalgamated with Community Memorial Hospital Port Perry to form North Durham Health Services (NDHS).

Though the hospital originally had 49 beds, the number has been reduced to 20.

Uxbridge Cottage also provides a 24-hour emergency department, primary care and some secondary care services to the township of Uxbridge.