The V-80 (German: Versuchs-U-Boot V 80) was a 76-ton experimental submarine and the only representative of the German Type V design produced for Nazi Germany's Kriegsmarine.

The prototype was completed in 1940 in Friedrich Krupp Germaniawerft in Kiel.

The four-man vessel was designed to test the Walter hydrogen peroxide-based turbine propulsion system.

Its range was 50 nmi (93 km; 58 mi) at 28 knots (52 km/h; 32 mph).

The only earlier attempt to use a chemical reaction based air-independent propulsion system was in the Spanish submarine the Ictineo II.