VE (S-(diethylamino)ethyl O-ethyl ethylphosphonothioate) is a "V-series" nerve agent closely related to the better-known VX nerve agent.

[1] Like most of the agents in the V-series (with the exception of VX), VE has not been extensively studied outside of military science.

[citation needed] It is commonly theorized that the so-called "second-generation" V series agents came from a Cold War era Russian chemical weapons development program.

They have similar lethal dose levels to VX (between 10–50 mg) and have similar symptoms and method of action to other nerve agents that act on cholinesterase, and treatment remains the same, but the window for effectively treating second generation V series seizures is shorter.

[citation needed] In addition to the standard seizures, some of the second generation V series agents are known to cause comas.