Vanessa Henke (born 15 January 1981), also known as Vanessa Paffrath, is a German former professional tennis player.

Henke took part in the qualifying for the 2006 Qatar Ladies Open, but lost in the second round.

She also participated at the 2007 Bank of the West Classic and many other ITF & WTA Tour events.

In 2003, she played one match for the Germany Fed Cup team.

Alongside Angelika Rösch she lost in the World Group play-offs against the pairing of Indonesian team in straight sets (overall Germany won 3–2).