On 28 October 2018, Chuang announced her retirement from pro tour and her marriage via Instagram.

At the 2007 Australian Open, Chuang reached the final of the women's doubles tournament with her partner Chan Yung-jan that they lost in three sets to Cara Black and Liezel Huber.

In 2001, Chuang played for the first time for the Chinese Taipei Fed Cup team.

Chuang's favorite surface is hardcourt, and her best shot is her serve.

She started playing tennis at age seven when introduced to it by her father.