Vanilla humblotii is a species of orchid endemic to Madagascar and the island of Grande Comore in the Comoros Islands.

They are an endangered species, with a low population caused by anthropogenic activity.

They live on dry, rocky mountains and in mesophilous forests.

Vanilla humblotii have no leaves and are characterized by canary yellow flowers with a red velvet lip.

[1] They are known to have applications in medicine due to its antimicrobial properties, so it is important to protect them for future use.