She starred as a lead actress in the Bollywood films, Ghar Aaya Mera Pardesi and Pathreela Raasta.

In the Faisal Saif-directed controversial Hindi feature film, Jigyaasa, she played the role of a "mother" to Hrishitaa Bhatt.

Usgaonkar started her television career in 1988 playing the role of Uttara, wife of Abhimanyu and mother of Parikshit, (the future of the Bharat Dynasty TV serial Mahabharata).

She has appeared in the Marathi shows Aakash Zep and Eka Mekansathi and has acted in the Hindi television serials Alvida Darling,[7] Tanha and Anhonee.

Usgaonkar is also a singer and has sung in a Konkani music album Roop Tujem Laita Pixem, with Ulhas Buyao.

[8] She is currently playing the supporting role of Nandini Yashwant Shirke-Patil in Star Pravah's popular serial Sukh Mhanje Nakki Kay Asta.