Lymphovascular invasion

Lymph: A clear or white fluid that travels through vessels, moves within tissues and work to keep all the parts of the body clean.

Lymphovascular invasion, especially in carcinomas, usually precedes spread to the lymph nodes that drain the tissue in which the tumour arose.

The absence of LVI in the context of proven lymph node metastasis is usually thought to be due to sampling error.

Whether LVI is a significant prognostic factor in breast cancer is widely debated, and there is no clear consensus.

[5][6] In urothelial carcinoma, LVI is an independent predictor of a poorer prognosis that has more predictive power than tumour stage.