Broadcaster Brent Musburger joined VSiN as lead on-air personality after his January 2017 departure from ESPN.

[2] VSiN opened a studio in the middle of the South Point Casino, with glass walls to be visible to fans on the floor.

[10] On September 1, 2023, VSiN announced that it would be moving out of the South Point casino and into a studio adjacent to BarCanada and the sports book at The D Las Vegas, which like Circa is owned by Derek Stevens and his family.

[13][14] Alongside Musburger, other on-air hosts employed by VSiN include Mitch Moss, Pauly Howard, Gill Alexander, Ron Flatter, Matt Youmans, Michael Lombardi, Tim Murray, Jonathan Von Tobel, Patrick Meagher, and Wes Reynolds.

VSiN also employs Nevada oddsmakers Jimmy Vaccaro, Vinny Magliulo, and Chris Andrews to appear on its broadcasts.