Venezuela competed at the 2020 Summer Paralympics in Tokyo, Japan, from 24 August to 5 September 2021.

[1][2] Guide: Alvaro Cassiani Five Venezuela athlete (Luis Felipe Rodriguez Bolivar, Edwars Alexander Varela Mesa, Lisbeli Marina Vera Andrade, Greilyz G. Villarroel Hernandez & Naibys Daniela Morillo Gil successfully to break through the qualifications for the 2020 Paralympics after breaking the qualification limit.

[3] DQ: Disqualified | SB: Season Best | Q: Qualified by place or standard based on overall position after heats | DNM: Did not mark | DNA: Did not advance | N/A: Not available, stage was not contested | PB: Personal Best | WR: World Record | PR: Paralympic Record | AR: Area Record Guide: Eubrig Maza Guide: Markinzon Manzanilla Guide: Edicson Medina Guide: Aris Antunez Venezuela sent one male cyclist after successfully getting a slot in the 2018 UCI Nations Ranking Allocation quota for the Americas.

[7][8] Venezuela entered one athletes into the table tennis competition at the games.

Denisos Martinez qualified from 2019 Parapan American Games which was held in Lima, Peru.