In particular, the clones of Trebbiano grown in Lombardy and Soave show very close similarities to Verdicchio while genetic evidence has shown that Greco was probably an ancestor vine to nearly all of Italy's native white grape varieties.

Castelli di Jesi, located around the commune of Iesi in the Ancona province, is the larger of the two areas and tends to produce a higher volume of wine.

According to wine expert Jancis Robinson, well made examples from favorable vintages can have flavors of lemons and slight bitter almond notes.

[4] Robinson also notes that the naturally high acidity of the grape makes it a good base cuvée variety for producing sparkling wine.

[6] The Verdicchio grapevine is very susceptible to clonal mutations with several sub-varieties of the grape known to exist in central Italy under various synonyms (see section below).