Rombo syndrome is a very rare genetic disorder characterized mainly by atrophoderma vermiculatum of the face,[2]: 580  multiple milia, telangiectases, acral erythema,[3] peripheral vasodilation with cyanosis,[4] and a propensity to develop basal cell carcinomas.

[3] The lesions become visible in late childhood, began at ages 7 to 10 years and are most pronounced on the face.

At that time a pronounced, somewhat cyanotic redness of the lips and hands was evident as well as moderate follicular atrophy of the skin on the cheeks.

[citation needed] In adults, the eyelashes and eyebrows were either missing or irregularly distributed with defective and maldirected growth.

After light irradiation a tendency to increased repair activity was observed both in epidermis and in the dermal fibroblasts.