Vermont Route 64 (VT 64) is a 6.770-mile-long (10.895 km) state highway in the U.S. state of Vermont.

Along the way, it intersects Interstate 89 (I-89) in Williamstown.

VT 64 begins at VT 12 in the town of Northfield.

The route proceeds to the east for about 2 miles (3.2 km), crossing into the town of Williamstown, then interchanges with I-89 at Exit 5.

VT 64 continues approximately 4 miles (6 km) to the east, ending at an intersection with VT 14 in Williamstown.