Born in Monessen, Pennsylvania, Wicker received a Bachelor of Fine Arts degree from Syracuse University in 1952 and a Bachelor of Laws from Loyola University New Orleans College of Law in 1966.

She was a law clerk to Judge Lansing Leroy Mitchell of the United States District Court for the Eastern District of Louisiana from 1966 to 1977.

[1] Wicker was a United States magistrate judge for the Eastern District of Louisiana, from 1977 to 1979.

On June 5, 1979, Wicker was nominated by President Jimmy Carter to a new seat on the United States District Court for the Eastern District of Louisiana created by 92 Stat.

Wicker served in that capacity until her death of cancer, on December 10, 1994, in New Orleans, Louisiana.