Vice presidents of Guyana is a political position in Guyana.

The Prime Minister of Guyana serves as the First Vice President and acts as the constitutional successor for the President of Guyana in case of a vacancy.

[1] Historically, other members of the cabinet have also been appointed as Vice Presidents, who can perform the functions of the President.

[2] Vice presidency was created in October 1980 when the executive presidency was created.

A history of the office holder follows.