Musically, Vice Versa consists of electropop and house tracks, reggaeton songs, Latin pop numbers, bolero lines, and Brazilian funk rhythms.

[17] is a romantic song about a girl who drives Alejandro crazy and makes his heart race, while the hopeless singer confesses he likes everything about her.

"Virtual Sex") is an erotic song about "overcoming distance, bringing the bodies together", with Alejandro exposing "some of his deepest fantasies".

"Clouds"), which is a reggaeton and pop song with elements of electronic music,[7][8] Alejandro declares his eternal love to the girl who has won his heart.

"That Nap ZzZz"),[12][32] features elements of R&B and reggaeton,[7] and is a romantic love song dedicated to Alejandro's girlfriend Rosalía.

"Heal Me") is a lofi hip hop reggaeton ballad,[37] with urban and tropical rhythms,[38][39] that narrates a love story referring to two relationships; the current one and the one from the past, which continues to leave its mark today.

"Unfocused") is a new wave, synth-pop, and funk song,[8][38] with elements of disco, pop, EDM, and deep house,[12][31][38] and finds the singer very confused after a relationship breakup, so that he barely even knows where he is.

[30][43] It reached number one in Dominican Republic,[44] as well as the top 15 in several other countries such as Argentina and Spain, and on Billboard's Hot Latin Songs in the United States.

[50] The track became a massive global hit,[16] reaching number one in Argentina,[45] Bolivia,[51] Chile,[52] Colombia,[53] Costa Rica,[54] Dominican Republic,[55] Ecuador,[56] El Salvador,[57] Guatemala,[58] Honduras,[59] Latin America,[60] Mexico,[61] Nicaragua,[62] Panama,[63] Paraguay,[64] Peru,[65] Puerto Rico,[66] Spain,[67] and Uruguay.

[47][71] The third single from Vice Versa, "Sexo Virtual" was released on June 25, 2021, accompanied by a Nuno Gomes directed music video, alongside the album.

[79] After going viral on TikTok and achieving commercial success,[80][81][82] "Cúrame" was sent to radio stations on August 27, 2021, as the fourth single from the album.

[116] Vice Versa was released for digital download and streaming by Sony Music Latin and Duars Entertainment on June 25, 2021.

[4][117] It featured a 17-second interlude, entitled "Track 4", consisting of electronic sounds and a robot voice repeating the word "loading".

[118] The former began on July 15, 2021 at the Enigma Night Club in Raleigh, North Carolina, and concluded on December 18, 2021, at the Fair Expo Center in Miami, with concerts throughout the United States, Mexico, Spain, Puerto Rico, and Dominican Republic.

[119][120][121] The Vice Versa Tour began on January 15, 2022, at the Crypto.com Arena in Los Angeles, and concluded on June 11, 2022, at the Parc del Fòrum in Barcelona, with 26 shows across the United States, Latin America, and Spain.

[132] On November 17, 2022, the singer gave a live performance of "Lejos del Cielo", "Más de Una Vez", "Desesperados", and "Punto 40" at the 23rd Annual Latin Grammy Awards.

Rolling Stone's Lucas Villa described the album as "great" and noted Alejandro's "versatility", starting that there is "no limits" to his "malleable flow" and that he "takes reggaeton into the future" with Vice Versa.

[8] Also in his review for The Fader, Villa praised Alejandro for taking his signature "genres to new worlds altogether", proving "his ability to write captivating songs regardless of the style he chooses".

"[6] An author of Genius admired the singer for "fearlessly" displaying his "adaptability", "craftwork", and "versatility" on the album, describing it as "a memorable rollercoaster ride": "VICE VERSA is a look into how the future of Latin music should be like; filled with hard-hitting pop beats, undeniable confidence, and addicting well-produced tracks that will undoubtedly leave their thread woven in history.

"[137] Jon Caramanica from The New York Times, named Alejandro "the most imaginative meta-reggaeton Latin pop star" and adored his "synthetically sweet and appealingly lush" vocals.

[138] Also from The New York Times, Isabelia Herrera celebrated the album for "embracing melody and an unflinching (but calculated) desire to implode the traditional structures of pop and reggaeton".

[7] NPR critic Stefanie Fernández labeled it "a record that sets the standard for what a massively successful Latin pop album can, and should, accomplish".

[139] Writing for Mondo Sonoro, Luis M. Maínez named Vice Versa "the best reggaeton album in recent years" and praised Alejandro's "particular and unmistakable style that until now no one has been able to copy".

He compared the album to "the most revolutionary styles in history", saying "all tracks flow into each other with precision and organicity, with Rauw's vocals making the electric shock that unites everything".

The critic highlighted "Sexo Virtual", "Cosa Guapa", "Desenfocao'", "La Old Skul", and "Aquel Nap ZzZz".

[135] Rolling Stone's Julyssa Lopez noted the singer's "thrillingly unpredictable breakthrough" and the album's "unexpected beat switches and sudden flashes of house, bolero, and Brazilian funk, morphs constantly", highlighting "Todo de Ti" as its "crowning jewel".

[42] Jason Lipshutz from Billboard stated that Vice Versa "serves as the progressive vision for Latin urban music that Alejandro wants to set forth from the A-list" and compared Alejandro with the American rapper and singer Doja Cat as he "comfortably sings and raps in equal measures, grabbing whatever instrumental arrangement is thrown his direction".